Cleaning and disinfecting ISO Class 5 cleanrooms like hospital pharmacies and compounding pharmacies in compliance with govt norms and regulations demands perpetually utilised protocols. Even if certain service requirements specify huge expenses, pharmacies can implement cleanroom cleaning protocols at much affordable rates.

Proper apparel, consistent cleaning routines and staff cooperation are the three essentials in this regard. This beginner’s guide to pharmacy cleanroom cleaning aims to provide an overview of the products, chemicals and tools used in the cleanroom, along with the standard procedures followed. So, stay tuned to this blog till the end to learn all about pharmacy cleanroom cleaning procedures.

Establishing a Doable Pharmacy Cleanroom Cleaning Routine

The most significant question is not who cleans your pharmacy but rather how eligible they are. Lapses in cleanroom cleaning protocols can result in serious contamination, and therefore, detailed training becomes compulsory. Once the training is over, periodic supervision is required to be certain that the cleaning is done as planned. Keeping records is equally significant to avoid paying fines.

Cleanroom Cleaning Protocols in Special Situations

In serious situations when contamination is discovered, you instruct your staff to perform the designed cleaning procedure multiple times unless you achieve the level of sterility and cleanliness needed for an ISO 5 pharmacy.

Triple clean: It involves sanitising the anteroom and critical area 3 times. First step is using a detergent-based cleaner for cleaning, followed by complete cleaning using 2 distinct disinfectants and finally with a sporicidal agent.

9-time clean: This means repeating the ‘triple clean’ process three times which is performed only in the worst cases of contamination.

What to Use for Cleaning a Pharmacy Cleanroom?

This involves two basic steps, cleaning and disinfecting, and they must be performed in the correct order for effective cleaning.

Cleaning

A surfactant solution or detergent effectively removes grease, grime and dust particles from the surface. You can use a sticky roller or a dry microfiber mop to get rid of debris from the floor.

Disinfecting

Sanitising is mandatory for a hospital pharmacy of a USP 797-compliant compounding pharmacy. But since many kinds of disinfectants are available, it can confuse beginners. Oxidising disinfectants kill spores, while non-oxidizing disinfectants are organism specific.

Examples of non-oxidizing agents are:

  • Alcohols
  • Phenolics
  • QAC (Quaternary Ammonium Compounds)

Oxidising Agents are:

  • Peracetic Acid
  • Halogens
  • Hydrogen peroxide

Cleanroom Spills

A lint-free wipe dipped in sterile water is necessary for wiping away spills in the ISO Class 5 area. Abide by the guidelines mentioned in the SOP for preventing chemical reactions between cleaning agents and pharmaceutical components. You can also use chemo prep mats for spill prevention.

Preparation of Pharmacy Cleanroom Cleaning Procedures

While diluting, handling, applying, and storing cleaning agents, abide by manufacturer instructions and follow this common procedure:

  • Mix right before using, and don’t forget to document the solutions’ preparation
  • Pre-measure the quantity of water into a plastic or glass bucket or cylinder and mix carefully to avoid spillage.
  • Use sterile water for ISO Class 5 areas. While tap water is fine for other surfaces/ areas.
  • Label the spray bottle with an expiration date and replace the solutions weekly with a fresh preparation.

You may also ask for MSDS (Material Safety Data Sheets) from the manufacturer of cleaning solutions, and you must keep the MSDS onsite.

Essential Cleaning Tools and Equipment

Now let’s discuss what you need to begin the pharmacy cleanroom cleaning.

1. Mops

To stop contamination, mops used for cleaning floors can’t be used for cleaning ceilings and walls. Similarly, equipment meant to clean a particular ISO Class area cannot be used to clean another class area. Investing in equipment of higher quality (like stainless steel mop handles, autoclavable bucketless cleanroom etc.) will not only reduce the number of appliances but also prove cheaper in the long run. Plus, advanced “systems” are user-friendly and time-saving.

2. PPE

PPE is a must for cleanroom cleaning staff as it protects them from critical environment resulting from particle or biological contamination as well as chemical splash:

  • Protective clothing like non-linting gowns and sterile coveralls
  • Surgical masks
  • Bouffant caps
  • Powder-free and disposable gloves
  • Safety glasses

3. Wipes

For cleaning ISO Class 5 or higher areas, we would recommend only lint-free wipes. Just keep in mind that pre-saturated wipes may have certain components that you can’t dispose of in unregulated trash. So, read the package carefully.

Cleaning Verifications

When cleaning or disinfecting, you are removing both viable particles (micro-organisms) and non-viable (non-living) particles. So, you must ensure proper removal of substances throughout the surroundings while testing, compounding and packaging substances that humans will use. Monitoring is essential for both viable and non-viable particles to determine the asepsis of the critical environment.

  • Sample the surrounding air for non-viable substances.
  • Test for yeast and bacteria by using contact plates to monitor the air for microbial contamination.

In addition to the above-mentioned guidance, connect with Trikon clinical waste Solution for detailed pharmacy cleanroom cleaning.

Developing Cleaning Protocols

The investment in equipment and facilities for effective cleanroom cleaning is surely important. But, all efforts will go in vain if the efficacy of the applications and processes isn’t maintained dedicatedly. Designing a proper cleanroom cleaning procedure requires educating staff and establishing policies. But explaining everything to your staff in detail, like cleanroom cleaning practices, equipment, tools, behaviours and procedures, will surely be a challenging task. On the other hand, authorised cleaning agencies like Trikon already have trained staff to perform such critical tasks.

Why Partner with Trikon Clinical Waste Solutions?

Trikon Clinical Waste Solutions’ is your one-stop destination to all types of professional cleaning, and our motto is to offer a safe and infection-free environment to everyone. Here’s how we can help you:

  • TCWS abides by all government guidelines in relation to pharmacy cleanroom cleaning in London and the UK.
  • TCWS has several years of experience in supplying clean rooms in the UK and has helped multiple pharmacies.
  • Trikon’s experienced staff has received detailed training on cleanroom cleaning protocol and can perform efficiently and in favour of environmental hygiene.
  • TCWS offers the lowest prices and flexible service options for pharmacy cleanroom cleaning.
  • TCWS also provides complimentary product samples to give you a glimpse of our cleanroom services.

Takeaway

Pharmacy cleanroom cleaning procedure is a complex multi-step process if you want to achieve perfection. From educating staff to designing a cleaning program, pharmacy cleanroom cleaning demands establishing a few procedures and policies.

If you require professional assistance with your cleanroom cleaning protocols, Trikon Clinical Waste Solutions is one call/ mail away. Contact us to learn more about our pharmacy cleanroom cleaning products, tactics and procedures.

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